alt. title - Midnight Detective - Nightwalker.
Having defeated the vampire lord Cain, Shido, a vampire turned private investigator, continues to battle to save humans from the macabre "nightbreeds" and other forces of darkness. As before, he is joined by the police detective Yayoi, the devil-sprite Guni, and his office aid, the former high school girl turned vampire Riho. Now Riho must deal with the terrible burden of being a vampire as she is forced to abandon the life she once knew. Shido must guide this new vampire while dealing with his own decision to grant Riho's dying request to become a vampire.